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VASCULITIS

VASCULITIS

Vessels are involved in most inflammatory processes in the human body. Vasculitis denotes conditions where vessels are the target of inflammation. The vasculitides can best be classified according to the size of vessels involved (Fig. 14-50).

Arteriole Venule Capillary

Small artery

Large to medium-sized

artery

Vein

HV

HSP

Microscopic polyangiitis

GPA

Aorta Vena cava

Polyarteritis nodosa

GCA

FIGURE 14-50 • Classification scheme for the vasculitides HV, hypersensitivity vasculitis; HSP, Henoch– Schönlein purpura; GPA, granulomatosis with polyangitis; GCA, giant cell arteritis. (Modified with permission from Jennette JC, et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994;37:187. ©1994 American College of Rheumatology.)