DIABETIC BULLAE
DIABETIC BULLAE ICD-10: E14.650
• Large, intact bullae arise spontaneously on the lower legs, feet, dorsa of the hands, and fingers on noninflamed bases (Fig. 15-1).
• Neither trauma nor an immunologic mechanism has been implicated. Histologically, bullae show intra- or subepidermal clefting without acantholysis.
FIGURE 15-1 • Diabetic bulla A large, intact bulla is seen on the pretibial skin on the right lower leg. The patient had many of the vascular complications of diabetes mellitus, i.e., renal failure, retinopathy, and atherosclerosis obliterans resulting in amputation of the left big toe. (Used with permission of Dr. Kenneth Greer.)