XANTHOMA TUBEROSUM
XANTHOMA TUBEROSUM ICD-10: E78.230
• This condition comprises yellowish nodules (Fig. 15-11) located especially on the elbows and knees by confluence of concomitant eruptive xanthomas.
• They are to be found in patients with FD (type III), familial hypertriglyceridemia with chylomicronemia (type V) and FH (Table 15-2).
• In homozygous patients with FH, the tuberous xanthomas are flatter and skin colored. They are not accompanied by eruptive xanthomas (see the following discussion).
• Management: Treatment of the underlying condition.
• Synonym: Tuberous xanthoma.

FIGURE 15-9 • Xanthelasma Multiple creamy-orange, slightly elevated dermal papules on the eyelids of a normolipemic individual.

FIGURE 15-10 • Tendinous xanthoma Large subcutaneous tumor adherent to the Achilles tendon.

FIGURE 15-11 • Tuberous xanthoma Flat-topped, yellow, firm nodule.

TABLE 15-2 Clinical Presentations of Xanthomas