๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
GROVER DISEASE (GD)
GROVER DISEASE (GD)ย ย ICD-10: L11.1
โข A pruritic dermatosis located principally on the trunk, occurring as crops of discrete papular or papulovesicular lesions, sparse to numerous (Fig. 5-5).
โข Occurs in adults (mean 50 years), males > females.
โข Pruritus is the main symptom.
โข Usually transient but a persistent form is recognized.
โข Precipitating factors: heavy, sweat-inducing exercise, exposure to solar radiation, heat, and persistent fever, also in bedridden patients.
โข Principal histopathologic feature: variable focal acantholysis and dyskeratosis.
โข No evidence of genetic predisposition.
โข Management: glucocorticosteroids under occlusion, UVB, or PUVA (photochemotherapy). Oral glucocorticosteroids, dapsone, and isotretinoin in refractory cases. Vitamin-D analogues may also be considered.
โข Synonym: transient acantholytic dermatosis.
FIGURE 5-5 โข Grover diseaseโA rash consisting of reddish, hyperkeratotic scaling, and/or crusted papules with a sandpaper feel upon palpation. Papules are discrete, scattered on the central trunk, and very pruritic.