CUTANEOUS T-CELL LYMPHOMA
CUTANEOUS T-CELL LYMPHOMA ICD-10: C84.0/C84.1
• Cutaneous T-cell lymphoma (CTCL) is a term that applies to T-cell lymphoma first manifested in the skin, but since the neoplastic process involves the entire lymphoreticular system, the lymph nodes and internal organs become involved in the course of the disease. CTCL is a malignancy of helper T cells (CD4+) but CD8+ predominant subtypes are also diagnosed.
• In the classic form of CTCL, called mycosis fungoides (MF), the malignant cells are cutaneous CD4+ cells, but the clinical entity of MF has now been expanded to the spectrum of CTCL including non-MF CTCLs.
• Whereas all MF is CTCL not all CTCLs are MF.
• Only the classic MF form is discussed here.