๐ ็ธฝ็ฎ้ ๏ฝ ๐ ่ฑๆๅๆ๏ผๆฌ็ฏ๏ผ ๏ฝ ๐ ๅฎๆด็ฟป่ญฏ ๏ฝ โญ ็ฒพ่ฏ็ญ่จ
CUTANEOUS DIPHTHERIA
CUTANEOUS DIPHTHERIAย ย ICD-10: A30
โข Etiology. Corynebacterium diphtheria. Cases in industrialized countries extremely rare.
โข Pathogenesis. Localized infection caused by toxigenic and nontoxigenic strains. Acute infection may involve any mucous membrane or skin wound. Toxin causes myocarditis and peripheral neuropathy.
โข Clinical Manifestations. Cutaneous: Nonspecific wound. Thick gray membrane in the pharynx. Myocarditis, arrhythmias. Polyneuritis involving cranial nerves: Diplopia, slurred speech, or difficulty swallowing.
โข Diagnosis. Made by isolation of C. diphtheria on the culture of the wound.
โข Treatment. Penicillin, erythromycin, or antitoxin. Vaccination. Immunity to vaccine wanes over time. Decennial boosters are recommended.